Prediction of Placental Barrier Permeability: A Model Based on Partial Least Squares Variable Selection Procedure

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Prediction of placental barrier permeability: a model based on partial least squares variable selection procedure.

Assessing the human placental barrier permeability of drugs is very important to guarantee drug safety during pregnancy. Quantitative structure-activity relationship (QSAR) method was used as an effective assessing tool for the placental transfer study of drugs, while in vitro human placental perfusion is the most widely used method. In this study, the partial least squares (PLS) variable selec...

متن کامل

Model selection for partial least squares regression

Partial least squares (PLS) regression is a powerful and frequently applied technique in multivariate statistical process control when the process variables are highly correlated. Selection of the number of latent variables to build a representative model is an important issue. A metric frequently used by chemometricians for the determination of the number of latent variables is that of Wold’s ...

متن کامل

Model selection for partial least squares based dimension reduction

0167-8655/$ see front matter 2011 Elsevier B.V. A doi:10.1016/j.patrec.2011.11.009 ⇑ Corresponding author. Address: Department of C Tongji University, Cao’an Road 4800, Shanghai 2018 3706; fax: +86 21 6958 9241. E-mail address: [email protected] (M. You). Partial least squares (PLS) has been widely applied to process scientific data sets as an effective dimension reduction technique. The main...

متن کامل

Variable selection in discriminant partial least-squares analysis.

Variable selection enhances the understanding and interpretability of multivariate classification models. A new chemometric method based on the selection of the most important variables in discriminant partial least-squares (VS-DPLS) analysis is described. The suggested method is a simple extension of DPLS where a small number of elements in the weight vector w is retained for each factor. The ...

متن کامل

A prediction model of compressor with variable-geometry diffuser based on elliptic equation and partial least squares

To achieve a much more extensive intake air flow range of the diesel engine, a variable-geometry compressor (VGC) is introduced into a turbocharged diesel engine. However, due to the variable diffuser vane angle (DVA), the prediction for the performance of the VGC becomes more difficult than for a normal compressor. In the present study, a prediction model comprising an elliptical equation and ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Molecules

سال: 2015

ISSN: 1420-3049

DOI: 10.3390/molecules20058270